Core-shell nanostructures
Prof. Alonso's team has developed core-shell nanostructures to confront mucosal barriers (image below). Some of these nanostructures are able to diffuse accross mucus barriers and penetrate into cells (image left)
Lipid nanocapsules
Novel functionalized cyclodextrin nanoparticles
Single multiple Pill - SmPill®
SmPill® is an innovative drug delivery technology developed at Sigmoid Pharma. It addresses in an integrative manner the issues formulators face when dealing with small molecules and biologics. Sigmoid is utilising SmPill to create novel therapeutics designed to address unmet clinical needs in a range of diseases as well as enabling oral vaccine and peptide delivery.
Nanoparticles interacting with the mucus
Nanoparticles in the intestine
Nanoparticles transport across the intestinal epithelium
Uppsala Universitiy will start its activity in the second half of 2013. The picture shows nanoparticle transport across the intestinal epithelium from an earlier project.
Identification of potential biomarker of toxicity using metabolomic approach
Dr. Mabondzo's group will use a metabolomic approach to build metabolomic maps pointing out the putative dysfuntions occurring during the interactions between epithelial cells and nanocarriers.
Veneto Nanotech-ECSIN activities in nanotoxicology
The main focus of Veneto Nanotech-ECSIN is to study the impact of engineered nanomaterials on human health and environment. In this context, cell biology, molecular biology, biochemistry, as well as fluorescent confocal and electron microscopy techniques are employed to unveil the interaction and effect of nanoparticles exposure to cells.
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